Formula 82M

A Uniquely Engineered Formulation Providing an Alternative Solution for Hair Loss


Minoxidil Sulfate is an active metabolite which has been shown in studies to stimulate hair growth. It has been the number one topical therapy for Androgenetic Alopecia (AGA) since receiving FDA clearance in the US in 1988. 

Formula 82M contains (5%) Minoxidil and Retinoic Acid, along with a 5-alpha reductase inhibitor and topical steroid to improve efficacy and reduce irritation, complimented by other proprietary ingredients that improve the formula's overall effectiveness, stability and usability.

Proposed mechanisms of action for Minoxidil:

  • Promotes Vasodilatation
  • Slows Senescence of Keratinocytes
  • Increases Proliferation of Dermal Papilla Cells in Hair Follicles
  • Enhances Cell Proliferation

Increased Efficacy With Retinoic Acid And Minoxidil

"So why does this product appear markedly more efficacious than others on the market such as Rogaine® and Propecia®? A review of product ingredients discussed in this article shows that higher strengths of Minoxidil (5%) are more effective than lower (2%). The addition of [Retinoic Acid] increases the efficacy of Minoxidil. A topical steroid improves efficacy and reduces irritation, and a 5-alpha reductase blocker increases efficacy. Formula 82M contains all of these previously proven ingredients and now in a Propylene Glycol-free base. However, more importantly, their proprietary solubilizing and stabilizing process appears to markedly improve drug delivery and shelf life."

— Dr. Mark G. Rubin
From 82M, A Uniquely Engineered Formulation Providing an Alternative Solution for Alopecia Patients

Some frequently asked questions about Formula 82M answered by one of our provider physicians, Dr. Aaron Shiloh at Shiloh Vein and Aesthetics.